GATA2 mutations and overexpression in pediatric acute myeloid leukemia

Background: GATA2 is important for the regulation of development and proliferation of early pluripotent hematopoietic precursors, and precise GATA2 expression is critical in myeloid lineage maturation. GATA2 mutations have been reported in acute myeloid leukemia (AML) but only few studies of GATA2 m...

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Bibliographic Details
Main Authors: Zhenzhen Yang, Xingjuan Wang, Xi Chen, Hu Dou, Yi Huang, Ling Lu, Lin Zou, Junqin Bi, Meng Su, Jie Yu, Liming Bao
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Pediatric Hematology Oncology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2468124519302463