Inhibition of adult neurogenesis reduces avoidance behavior in male, but not female, mice subjected to early life adversity

Early life adversity (ELA) increases the risk of developing neuropsychiatric illnesses such as anxiety disorders. However, the mechanisms connecting these negative early life experiences to illness later in life remain unclear. In rodents, plasticity mechanisms, specifically adult neurogenesis in th...

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Bibliographic Details
Main Authors: Renée C. Waters, Hunter M. Worth, Betsy Vasquez, Elizabeth Gould
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Neurobiology of Stress
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235228952200011X