Neutralization of botulinum neurotoxin by a human monoclonal antibody specific for the catalytic light chain.

Neutralization of botulinum neurotoxin by a human monoclonal antibody specific for the catalytic light chain.

Botulinum neurotoxins (BoNT) are a family of category A select bioterror agents and the most potent biological toxins known. Cloned antibody therapeutics hold considerable promise as BoNT therapeutics, but the therapeutic utility of antibodies that bind the BoNT light chain domain (LC), a metallopro...

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Bibliographic Details
Main Authors: Sharad P Adekar, Tsuyoshi Takahashi, R Mark Jones, Fetweh H Al-Saleem, Denise M Ancharski, Michael J Root, B P Kapadnis, Lance L Simpson, Scott K Dessain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2515629?pdf=render

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http://europepmc.org/articles/PMC2515629?pdf=render

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