Generation of beta-lactoglobulin knock-out goats using CRISPR/Cas9.

Generation of beta-lactoglobulin knock-out goats using CRISPR/Cas9.

Goat's milk, considered a substitute for cow's milk, has a high nutritional value. However, goat's milk contains various allergens, predominantly β-lactoglobulin (BLG). In this study, we employed the CRISPR/Cas9 system to target the BLG locus in goat fibroblasts for sgRNA optimization...

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Bibliographic Details
Main Authors: Wenjun Zhou, Yongjie Wan, Rihong Guo, Mingtian Deng, Kaiping Deng, Zhen Wang, Yanli Zhang, Feng Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5634636?pdf=render

Internet

http://europepmc.org/articles/PMC5634636?pdf=render

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