Using genetic instruments to estimate the causal effect of hormonal reproductive factors on osteoarthritis

ObjectivesHormonal reproductive factors have been considered to play an important role in the etiology of osteoarthritis (OA). We performed Mendelian randomization (MR) to examine whether a causal effect existed between them.MethodsMR was performed by using publicly released genome-wide association...

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Bibliographic Details
Main Authors: Bingran Wang, Junhua Wu, Han Li, Xiaoyan Jin, Cong Sui, Zhen Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.941067/full