Correlating CpG islands, motifs, and sequence variants in human chromosome 21
<p>Abstract</p> <p>Background</p> <p>CpG islands are important regions in DNA. They usually appear at the 5’ end of genes containing GC-rich dinucleotides. When DNA methylation occurs, gene regulation is affected and it sometimes leads to carcinogenesis. We propose a ne...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2011-07-01
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| Series: | BMC Genomics |