In Vitro Studies of Squalene‐Gusperimus Nanoparticles in Islet‐Containing Alginate Microcapsules to Regulate the Immune Response in the Immediate Posttransplant Period

In Vitro Studies of Squalene‐Gusperimus Nanoparticles in Islet‐Containing Alginate Microcapsules to Regulate the Immune Response in the Immediate Posttransplant Period

Grafting of microencapsulated pancreatic islets has been proposed as an alternative to exogenous insulin for the treatment of type 1 diabetes mellitus. Microencapsulated islets are protected from direct contact with immune cells and larger immune‐active molecules such as immunoglobulins. Unfortunate...

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Bibliographic Details
Main Authors: Carlos E. Navarro Chica, Tian Qin, Bart J. de Haan, Marijke M. Faas, Alexandra M. Smink, Ligia Sierra, Betty L. López, Paul de Vos
Format: Article
Language:English
Published: Wiley-VCH 2021-11-01
Series:Advanced NanoBiomed Research
Subjects:
alginate microcapsules
gusperimus controlled release
islet microencapsulation
local immunosuppression
squalene-gusperimus nanoparticles
type 1 diabetes mellitus
Online Access:https://doi.org/10.1002/anbr.202100055

Internet

https://doi.org/10.1002/anbr.202100055

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