Single-cell sequencing analysis fibrosis provides insights into the pathobiological cell types and cytokines of radiation-induced pulmonary fibrosis

Single-cell sequencing analysis fibrosis provides insights into the pathobiological cell types and cytokines of radiation-induced pulmonary fibrosis

Abstract Background Radiotherapy is an essential treatment for chest cancer. Radiation-induced pulmonary fibrosis (RIPF) is an almost irreversible interstitial lung disease; however, its pathogenesis remains unclear. Methods We analyzed specific changes in cell populations and potential markers by u...

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Bibliographic Details
Main Authors: Zhiyong Sun, Yutao Lou, Xiaoping Hu, Feifeng Song, Xiaowei Zheng, Ying Hu, Haiying Ding, Yiwen Zhang, Ping Huang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Pulmonary Medicine
Subjects:
Radiation-induced pulmonary fibrosis
Single-cell RNA-seq
T cells
B cells
Online Access:https://doi.org/10.1186/s12890-023-02424-5

Internet

https://doi.org/10.1186/s12890-023-02424-5

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