Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.

Human schistosomiasis is a neglected tropical disease caused by Schistosoma mansoni, S. haematobium, and S. japonicum. Praziquantel (PZQ) is the method of choice for treatment. Due to constant selection pressure, there is an urgent need for new therapies for schistosomiasis. Previous treatment of S....

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Bibliographic Details
Main Authors: Sevan N Alwan, Alexander B Taylor, Jayce Rhodes, Michael Tidwell, Stanton F McHardy, Philip T LoVerde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-07-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011018&type=printable