Cross-Sectional and Longitudinal MRI Brain Scans Reveal Accelerated Brain Aging in Multiple Sclerosis

Cross-Sectional and Longitudinal MRI Brain Scans Reveal Accelerated Brain Aging in Multiple Sclerosis

Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system. By combining longitudinal MRI-based brain morphometry and brain age estimation using machine learning, we tested the hypothesis that MS patients have higher brain age relative to chronological age than healthy control...

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Bibliographic Details
Main Authors: Einar A. Høgestøl, Tobias Kaufmann, Gro O. Nygaard, Mona K. Beyer, Piotr Sowa, Jan E. Nordvik, Knut Kolskår, Geneviève Richard, Ole A. Andreassen, Hanne F. Harbo, Lars T. Westlye
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
brain age
magnetic resonance imaging
machine learning
longitudinal
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00450/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00450/full

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