A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls

A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls

Abstract Increased leucine‐rich repeat kinase 2 (LRRK2) kinase activity is an established risk factor for Parkinson's disease (PD), and several LRRK2 kinase inhibitors are in clinical development as potential novel disease‐modifying therapeutics. This biomarker characterization study explored w...

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Bibliographic Details
Main Authors: Maurits F. J. M. Vissers, Matthew D. Troyer, Eva Thijssen, Diana R. Pereira, | Jules A. A. C. Heuberger, Geert Jan Groeneveld, Sarah Huntwork‐Rodriguez
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13541

Internet

https://doi.org/10.1111/cts.13541

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