Photoswitchable TRPC6 channel activators evoke distinct channel kinetics reflecting different gating behaviors

Photoswitchable TRPC6 channel activators evoke distinct channel kinetics reflecting different gating behaviors

Summary: The non-selective transient receptor potential canonical 6 (TRPC6) cation channels have several physiological and pathophysiological effects. They are activated by the lipid second messenger diacylglycerol (DAG) and by non-lipidic compounds such as GSK 1702934A (GSK). Advances in photopharm...

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Bibliographic Details
Main Authors: Maximilian Keck, Christian Hermann, Kyra Lützel, Thomas Gudermann, David B. Konrad, Michael Mederos y Schnitzler, Ursula Storch
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:iScience
Subjects:
Biophysical chemistry
Biological sciences
Biophysics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224022338

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224022338

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