Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced schizophrenia in mice

Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced schizophrenia in mice

Inhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation can provide normalization of neurochemical homeostasis and neurotrophic support in the pathogenesis of psychiatric disorders with complex symptoms such as schizophrenia. Accordingly, the preventive and reversal...

Full description

Bibliographic Details
Main Authors: Benneth Ben-Azu, Olusegun G. Adebayo, Aliance R. Fokoua, Jackson E. Onuelu, Jerome N. Asiwe, Emuesiri G. Moke, Itivere A. Omogbiya, Oghenemarho L. Okpara, Jennifer E. Okoro, Omadevuaye M. Oghenevwerutevwe, Christian I. Uruaka
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Brain Disorders
Subjects:
Schizophrenia
Neuroinflammation
Dopamine
Cognitive symptoms
Diosgenin
Online Access:http://www.sciencedirect.com/science/article/pii/S2666459324000076

Internet

http://www.sciencedirect.com/science/article/pii/S2666459324000076

Similar Items