Asynchronous Onset of Clinical Disease in BSE-Infected Macaques

To estimate the effect of the variability of prion disease onset on primary bovine spongiform encephalopathy transmission to humans, we studied 6 cynomolgus macaques. The preclinical incubation period was significantly prolonged in 2 animals, implying that onset of variant Creutzfeldt-Jacob disease...

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Bibliographic Details
Main Authors: Judith Montag, Walter Schulz-Schaeffer, Annette Schrod, Gerhard Hunsmann, Dirk Motzkus
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2013-07-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/19/7/12-0438_article