Avocado: a multi-scale deep tensor factorization method learns a latent representation of the human epigenome

Abstract The human epigenome has been experimentally characterized by thousands of measurements for every basepair in the human genome. We propose a deep neural network tensor factorization method, Avocado, that compresses this epigenomic data into a dense, information-rich representation. We use th...

Full description

Bibliographic Details
Main Authors: Jacob Schreiber, Timothy Durham, Jeffrey Bilmes, William Stafford Noble
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-020-01977-6