Calorie restriction improves lipid-related emerging cardiometabolic risk factors in healthy adults without obesity: Distinct influences of BMI and sex from CALERIE™ a multicentre, phase 2, randomised controlled trial

Summary: Background: For many cardiovascular risk factors there is no lower limit to which further reduction will result in decreased disease risk; this includes values within ranges considered normal for healthy adults. This seems to be true for new emerging metabolic risk factors identified by in...

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Main Authors: Kim M. Huffman, Daniel C. Parker, Manjushri Bhapkar, Susan B. Racette, Corby K. Martin, Leanne M. Redman, Sai Krupa Das, Margery A. Connelly, Carl F. Pieper, Melissa Orenduff, Leanna M. Ross, Megan E. Ramaker, James L. Dorling, Clifford J Rosen, Irina Shalaurova, James D. Otvos, Virginia B. Kraus, William E. Kraus
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:EClinicalMedicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021005423