Nucleus Accumbens Shell and mPFC but not Insula Orexin-1 Receptors Promote Excessive Alcohol Drinking

Addiction to alcohol remains a major social and economic problem, in part because of the high motivation for alcohol that humans exhibit and the hazardous binge intake this promotes. Orexin-1-type receptors (OX1Rs) promote reward intake under conditions of strong drives for reward, including excessi...

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Bibliographic Details
Main Authors: Kelly Lei, Scott Wegner, JiHwan Yu, Arisa Mototake, Bing Hu, Frederic Hopf
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00400/full