Fecal microbiota transplanted from old mice promotes more colonic inflammation, proliferation, and tumor formation in azoxymethane-treated A/J mice than microbiota originating from young mice

Fecal microbiota transplanted from old mice promotes more colonic inflammation, proliferation, and tumor formation in azoxymethane-treated A/J mice than microbiota originating from young mice

ABSTRACTAging is a strong risk factor for colorectal cancer (CRC). It is well established that gut microbial dysbiosis can play a role in the etiology of CRC. Although the composition of the gut microbial community changes with age and is reported to become more pro-inflammatory, it is unclear wheth...

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Bibliographic Details
Main Authors: Nicholas A. Crossland, Samuel Beck, Wei Yu Tan, Ming Lo, Joel B. Mason, Chao Zhang, Weimin Guo, Jimmy W. Crott
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Microbiome
fecal microbiota transplant (FMT)
aging
colorectal cancer (CRC)
mitochondria
inflammation
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2288187

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2023.2288187

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