Direct detection of drug-resistant Mycobacterium tuberculosis using targeted next generation sequencing

Direct detection of drug-resistant Mycobacterium tuberculosis using targeted next generation sequencing

Mycobacterium tuberculosis complex (MTBC) infections are treated with combinations of antibiotics; however, these regimens are not as efficacious against multidrug and extensively drug resistant MTBC. Phenotypic (growth-based) drug susceptibility testing on slow growing bacteria like MTBC requires m...

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Bibliographic Details
Main Authors: Shannon G. Murphy, Carol Smith, Pascal Lapierre, Joseph Shea, Kruthikaben Patel, Tanya A. Halse, Michelle Dickinson, Vincent Escuyer, Marie Claire Rowlinson, Kimberlee A. Musser
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Public Health
Subjects:
mycobacterium
tuberculosis
drug susceptibility
resistance
targeted sequencing
nanopore
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1206056/full

Internet

https://www.frontiersin.org/articles/10.3389/fpubh.2023.1206056/full

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