Prospective identification of malaria parasite genes under balancing selection.

BACKGROUND:Endemic human pathogens are subject to strong immune selection, and interrogation of pathogen genome variation for signatures of balancing selection can identify important target antigens. Several major antigen genes in the malaria parasite Plasmodium falciparum have shown such signatures...

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Detalles Bibliográficos
Main Authors: Kevin K A Tetteh, Lindsay B Stewart, Lynette Isabella Ochola, Alfred Amambua-Ngwa, Alan W Thomas, Kevin Marsh, Gareth D Weedall, David J Conway
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC2679211?pdf=render