Balanced crystalloids (RInger’s lactate) versus normal Saline in adults with diabetic Ketoacidosis in the Emergency Department (BRISK-ED): a protocol for a pilot randomized controlled trial

Balanced crystalloids (RInger’s lactate) versus normal Saline in adults with diabetic Ketoacidosis in the Emergency Department (BRISK-ED): a protocol for a pilot randomized controlled trial

Abstract Background Current guidelines for diabetic ketoacidosis (DKA) recommend treatment with normal saline (NS). However, NS, with its high chloride concentrations, may worsen acidosis and contribute to a hyperchloremic metabolic acidosis. Alternatives to NS are balanced crystalloids (e.g. Ringer...

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Bibliographic Details
Main Authors: Justin W. Yan, Ahmed Slim, Kristine Van Aarsen, Yun-Hee Choi, Christopher Byrne, Naveen Poonai, Haley Collins, Kristin K. Clemens
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Pilot and Feasibility Studies
Subjects:
Diabetic ketoacidosis
Balanced crystalloids
Normal saline
Emergency department
Pilot study
Randomized controlled trial
Online Access:https://doi.org/10.1186/s40814-023-01356-5

Internet

https://doi.org/10.1186/s40814-023-01356-5

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