Enhanced Functional Maturation of Fetal Porcine Hepatocytes in Three-Dimensional Poly-L-lactic Acid Scaffolds: A Culture Condition Suitable for Engineered Liver Tissues in Large-Scale Animal Studies

To engineer liver tissues with a clinically significant size, in vivo evaluation of performance using large-scale animal studies are necessary before proceeding to human clinical trials. As pigs are the most suitable candidates, the development of culture conditions suitable for porcine hepatocyte p...

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Bibliographic Details
Main Authors: Hongyun Huang, Sanshiro Hanada, Nobuhiko Kojima, Yasuyuki Sakai
Format: Article
Language:English
Published: SAGE Publishing 2006-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000006783981486