In vitro evaluation, in silico studies and toxicological assay of some xanthones as potential Leishmania donovani inhibitors

In vitro evaluation, in silico studies and toxicological assay of some xanthones as potential Leishmania donovani inhibitors

Xanthones are naturally occurring compounds that exist in some higher plants, fungi and lichen. Natural and synthetic xanthones have shown diverse biological and pharmacological properties. Thus, the present study was designed to examine the antileishmanial activity of five xanthone analogues, their...

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Bibliographic Details
Main Authors: Marwa S. Osman, Shaza W. Shantier, Talal A. Awad, Elrashied A.E. Garelnabi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Leishmania donovani
Xanthones
ADME
Cytotoxicity
QSPR
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914822001009

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http://www.sciencedirect.com/science/article/pii/S2352914822001009

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