Protein complexes in cells by AI‐assisted structural proteomics

Protein complexes in cells by AI‐assisted structural proteomics

Abstract Accurately modeling the structures of proteins and their complexes using artificial intelligence is revolutionizing molecular biology. Experimental data enable a candidate‐based approach to systematically model novel protein assemblies. Here, we use a combination of in‐cell crosslinking mas...

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Bibliographic Details
Main Authors: Francis J O'Reilly, Andrea Graziadei, Christian Forbrig, Rica Bremenkamp, Kristine Charles, Swantje Lenz, Christoph Elfmann, Lutz Fischer, Jörg Stülke, Juri Rappsilber
Format: Article
Language:English
Published: Springer Nature 2023-04-01
Series:Molecular Systems Biology
Subjects:
AlphaFold‐Multimer
crosslinking mass spectrometry
protein–protein interactions
pyruvate dehydrogenase
uncharacterized proteins
Online Access:https://doi.org/10.15252/msb.202311544

Internet

https://doi.org/10.15252/msb.202311544

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