Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method

According to the predominant theories, soluble amyloid-beta (Aβ) aggregates are the principal neurotoxic agents in Alzheimer’s disease pathology, making them a popular target for the development of therapeutics and diagnostic markers. One of the most commonly used methods for determining the concent...

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Bibliographic Details
Main Authors: Leen Janssen, Frank Sobott, Peter P. De Deyn, Debby Van Dam
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221501611500014X