Associations of Sperm mtDNA Copy Number, DNA Fragmentation Index, and Reactive Oxygen Species With Clinical Outcomes in ART Treatments

Associations of Sperm mtDNA Copy Number, DNA Fragmentation Index, and Reactive Oxygen Species With Clinical Outcomes in ART Treatments

Recent studies have suggested that sperm mitochondrial DNA copy number (mtDNA-CN), DNA fragmentation index (DFI), and reactive oxygen species (ROS) content are crucial to sperm function. However, the associations between these measurements and embryo development and pregnancy outcomes in assisted re...

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Bibliographic Details
Main Authors: Wei-Hui Shi, Mu-Jin Ye, Ning-Xin Qin, Zhi-Yang Zhou, Xuan-You Zhou, Nai-Xin Xu, Song-Chang Chen, Shu-Yuan Li, Chen-Ming Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
Subjects:
sperm mitochondrial DNA copy number
DNA fragmentation index
reactive oxygen species
sperm quality
assisted reproductive technology
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.849534/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.849534/full

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