Age-related changes in antigen-specific natural antibodies are influenced by sex

IntroductionNatural antibody (NAb) derived from CD5+ B-1 cells maintains tissue homeostasis, controls inflammation, aids in establishing long-term protective responses against pathogens, and provides immediate protection from infection. CD5+ B-1 cell NAbs recognize evolutionarily fixed epitopes, suc...

Full description

Bibliographic Details
Main Authors: Sarah E. Webster, Naomi L. Tsuji, Michael J. Clemente, Nichol E. Holodick
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1047297/full