Age-related changes in antigen-specific natural antibodies are influenced by sex
IntroductionNatural antibody (NAb) derived from CD5+ B-1 cells maintains tissue homeostasis, controls inflammation, aids in establishing long-term protective responses against pathogens, and provides immediate protection from infection. CD5+ B-1 cell NAbs recognize evolutionarily fixed epitopes, suc...
Main Authors: | Sarah E. Webster, Naomi L. Tsuji, Michael J. Clemente, Nichol E. Holodick |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-01-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1047297/full |
Similar Items
-
B cell extracellular vesicles contain monomeric IgM that binds antigen and enters target cells
by: Michael F. Gutknecht, et al.
Published: (2023-09-01) -
Atypical response of B-1 cells to BCR Ligation: A speculative model
by: Nichol E Holodick, et al.
Published: (2013-12-01) -
Expansion of B-1a cells with germline heavy chain sequence in lupus mice
by: Nichol E Holodick, et al.
Published: (2016-03-01) -
Secreted IgM deficiency alters the retinal landscape enhancing neurodegeneration associated with aging
by: Sarah E. Webster, et al.
Published: (2025-02-01) -
B-CD8+ T Cell Interactions in the Anti-Idiotypic Response against a Self-Antibody
by: Darel Martínez, et al.
Published: (2017-01-01)