Exploration of the Tumor Mutational Burden as a Prognostic Biomarker and Related Hub Gene Identification in Prostate Cancer

To explore the signature function of the tumor mutational burden (TMB) and potential biomarkers in prostate cancer (PCa), transcriptome profiles, somatic mutation data, and clinicopathologic feature information were downloaded from The Cancer Genome Atlas (TCGA) database. R software package was used...

Full description

Bibliographic Details
Main Authors: Licheng Wang MM, Yicong Yao MM, Chengdang Xu MM, Xinan Wang MM, Denglong Wu MD, PhD, Zhe Hong MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2021-11-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338211052154