DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease

DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease

Parkinson's disease (PD) is caused by dopaminergic cell death in the substantia nigra, leading to a reduced level of dopamine in the striatum. Oxidative stress is one of the causes of PD. Since symptomatic PD therapies are used, identification of compounds or proteins that inhibit oxidative str...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Kazuko Takahashi-Niki, Ayako Inafune, Naruyuki Michitani, Yoshitaka Hatakeyama, Kotaro Suzuki, Mai Sasaki, Yoshihisa Kitamura, Takeshi Niki, Sanae M.M. Iguchi-Ariga, Hiroyoshi Ariga
स्वरूप: लेख
भाषा:English
प्रकाशित: Elsevier 2015-03-01
श्रृंखला:Journal of Pharmacological Sciences
विषय:
Parkinson's disease
DJ-1
Compound
MPTP
Neuroprotection
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S1347861315000390

इंटरनेट

http://www.sciencedirect.com/science/article/pii/S1347861315000390

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