Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa

Summary: The Btla inhibitory receptor limits innate and adaptive immune responses, both preventing the development of autoimmune disease and restraining anti-viral and anti-tumor responses. It remains unclear how the functions of Btla in diverse lymphocytes contribute to immunoregulation. Here, we s...

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Bibliographic Details
Main Authors: Caroline Stienne, Richard Virgen-Slane, Lisa Elmén, Marisol Veny, Sarah Huang, Jennifer Nguyen, Elizabeth Chappell, Mary Olivia Balmert, Jr-Wen Shui, Michelle A. Hurchla, Mitchell Kronenberg, Scott N. Peterson, Kenneth M. Murphy, Carl F. Ware, John R. Šedý
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722002972