Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa
Summary: The Btla inhibitory receptor limits innate and adaptive immune responses, both preventing the development of autoimmune disease and restraining anti-viral and anti-tumor responses. It remains unclear how the functions of Btla in diverse lymphocytes contribute to immunoregulation. Here, we s...
Main Authors: | Caroline Stienne, Richard Virgen-Slane, Lisa Elmén, Marisol Veny, Sarah Huang, Jennifer Nguyen, Elizabeth Chappell, Mary Olivia Balmert, Jr-Wen Shui, Michelle A. Hurchla, Mitchell Kronenberg, Scott N. Peterson, Kenneth M. Murphy, Carl F. Ware, John R. Šedý |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-03-01
|
Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124722002972 |
Similar Items
-
GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity
by: Theresa E.H. Bierling, et al.
Published: (2024-02-01) -
Long-lasting humoral and cellular memory immunity to vaccinia virus Tiantan provides pre-existing immunity against mpox virus in Chinese population
by: Min Li, et al.
Published: (2024-01-01) -
MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity
by: Theresa E. Pankhurst, et al.
Published: (2023-04-01) -
Ly6C+ monocytes in the skin promote systemic alphavirus dissemination
by: Autumn C. Holmes, et al.
Published: (2024-03-01) -
Genetic determinants of complement activation in the general population
by: Damia Noce, et al.
Published: (2024-01-01)