Associations between HIFs and tumor immune checkpoints: mechanism and therapy

Abstract Hypoxia, which activates a variety of signaling pathways to enhance tumor cell growth and metabolism, is among the primary features of tumor cells. Hypoxia-inducible factors (HIFs) have a substantial impact on a variety of facets of tumor biology, such as epithelial-mesenchymal transition,...

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Bibliographic Details
Main Authors: Jiayu Liu, Ying Jiang, Lingyan Chen, Zhiwen Qian, Yan Zhang
Format: Article
Language:English
Published: Springer 2024-01-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00836-7