Reduction of blood C-reactive protein concentration complements the resolution of sputum bacillary load in patients on anti-tuberculosis therapy

Reduction of blood C-reactive protein concentration complements the resolution of sputum bacillary load in patients on anti-tuberculosis therapy

BackgroundTuberculosis (TB) is a difficult-to-treat disease requiring the combination of four antibiotics for a minimum of 6 months. Rapid and quantitative biomarkers to monitor treatment response are urgently needed for individual patient management and clinical trials. C-reactive protein (CRP) is...

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Bibliographic Details
Main Authors: Khalide Azam, Celso Khosa, Sofia Viegas, Isabel Massango, Nilesh Bhatt, Ilesh Jani, Norbert Heinrich, Michael Hoelscher, Stephen H. Gillespie, Andrea Rachow, Wilber Sabiiti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
bacillary load
tuberculosis molecular bacterial load assay
C-reactive protein
treatment response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1005692/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1005692/full

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