Cryopreserved Ex Vivo-Expanded Allogeneic Myeloid Progenitor Cell Product Protects Neutropenic Mice from a Lethal Fungal Infection

Severe neutropenia induced by chemotherapy or conditioning for hematopoietic cell transplantation often results in morbidity and mortality due to infection by opportunistic pathogens. A system has been developed to generate ex vivo-expanded mouse myeloid progenitor cells (mMPCs) that produce functio...

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Bibliographic Details
Main Authors: Jos Domen, Julie L. Christensen, Daphne Gille, Stephanie Smith-Berdan, Timothy Fong, Janice M. Y. Brown, Anna K. Sedello
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368915X687688