The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

Most deaths from solid cancers occur as a result of secondary metastasis to distant sites. Bone is the most frequent metastatic site for many cancer types and can account for up to 80% of cancer-related deaths in certain tumours. The progression from a discrete solid primary tumour to devastating an...

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Bibliographic Details
Main Authors: Alison Gartland, Janine T. Erler, Thomas R. Cox
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Bone Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137416300094