The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis
Most deaths from solid cancers occur as a result of secondary metastasis to distant sites. Bone is the most frequent metastatic site for many cancer types and can account for up to 80% of cancer-related deaths in certain tumours. The progression from a discrete solid primary tumour to devastating an...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Journal of Bone Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137416300094 |