Pseudomonas aeruginosa adaptation in cystic fibrosis patients increases C5a levels and promotes neutrophil recruitment

Cystic fibrosis (CF) disease is characterized by an intense airway inflammatory response mediated by neutrophils and chronic respiratory infections caused by P. aeruginosa. High levels of the complement component C5a, the strongest neutrophil chemoattractant molecule, are commonly found in the CF lu...

Full description

Bibliographic Details
Main Authors: Margalida Mateu-Borrás, Alex González-Alsina, Antonio Doménech-Sánchez, Javier Querol-García, Francisco J. Fernández, Mª Cristina Vega, Sebastián Albertí
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2022.2028484