The role of ARHGAP9: clinical implication and potential function in acute myeloid leukemia

Abstract Background Rho GTPase activating protein 9 (ARHGAP9) is expressed in various types of cancers and can inactivate Rho GTPases that mainly regulate cytoskeletal dynamics. However, the exact role of ARHGAP9 in acute myeloid leukemia (AML) has yet to be clarified. Methods We compared the transc...

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Bibliographic Details
Main Authors: Caixia Han, Shujiao He, Ruiqi Wang, Xuefeng Gao, Hong Wang, Jingqiao Qiao, Xiangyu Meng, Yonghui Li, Li Yu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-021-02733-5