The Mycobacterium tuberculosis PE15/PPE20 complex transports calcium across the outer membrane.

The mechanisms by which nutrients traverse the Mycobacterium tuberculosis (Mtb) outer membrane remain mostly unknown and, in the absence of classical porins, likely involve specialized transport systems. Calcium ions (Ca2+) are an important nutrient and serve as a second messenger in eukaryotes, but...

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Bibliographic Details
Main Authors: Vishant Boradia, Andrew Frando, Christoph Grundner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001906