NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4

NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4

Abstract Chronic inflammation plays a key role in development of many liver diseases. Stimulation of Toll-like receptor 4 (TLR4) by bacterial lipopolysaccharide (LPS) initiates inflammation and promotes development of hepatocellular carcinoma and other liver diseases. NADPH oxidases contribute to LP...

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Bibliographic Details
Main Authors: Anand Singh, Bhargav Koduru, Cameron Carlisle, Hasina Akhter, Rui-Ming Liu, Katrin Schroder, Ralf P. Brandes, David M. Ojcius
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-14574-8

Internet

https://doi.org/10.1038/s41598-017-14574-8

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