In vitro reconstitution of herpes simplex virus 1 fusion identifies low pH as a fusion co-trigger
ABSTRACTMembrane fusion mediated by herpes simplex virus 1 (HSV-1) is a complex, multi-protein process that is receptor triggered and can occur both at the cell surface and in endosomes. To deconvolute this complexity, we reconstituted HSV-1 fusion with synthetic lipid vesicles in vitro. Using this...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-12-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.02087-23 |