Affected albumin endocytosis as a new neurotoxicity mechanism of amyloid beta
Senile plaques, a hallmark of Alzheimer's disease, are composed by Amyloid-Beta (Aβ). Aβ 25-35 toxicity is caused mainly by increasing reactive oxygen species (ROS), which is reversed by albumin preventing Aβ internalization. In addition, key cellular processes and basic cell functions require...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2020-12-01
|
| Series: | AIMS Neuroscience |
| Subjects: | |
| Online Access: | http://www.aimspress.com/article/doi/10.3934/Neuroscience.2020021?viewType=HTML |