Molecular annotation of G protein variants in a neurological disorder

Molecular annotation of G protein variants in a neurological disorder

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Summary: Heterotrimeric G proteins transduce extracellular chemical messages to generate appropriate intracellular responses. Point mutations in GNAO1, encoding the G protein αo subunit, have been implicated in a pathogenic condition characterized by seizures, movement disorders, intellectual disabi...

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Bibliographic Details
Main Authors: Kevin M. Knight, Elizabeth G. Obarow, Wenyuan Wei, Sepehr Mani, Maria I. Esteller, Meng Cui, Ning Ma, Sarah A. Martin, Emily Brinson, Natalie Hewitt, Gaby M. Soden, Diomedes E. Logothetis, Nagarajan Vaidehi, Henrik G. Dohlman
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
CP: Neuroscience
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723014742

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723014742

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