Involvement of POMC neurons in LEAP2 regulation of food intake and body weight

Involvement of POMC neurons in LEAP2 regulation of food intake and body weight

Liver-expressed antimicrobial peptide 2 (LEAP2) is a newly discovered antagonist of the growth hormone secretagogue receptor (GHSR) and is considered the first endogenous peptide that can antagonize the metabolic actions of ghrelin. The effects of ghrelin administration on feeding behavior, body wei...

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Bibliographic Details
Main Authors: Guangpin Chu, Hualing Peng, Nana Yu, Yuejin Zhang, Xueling Lin, Yisheng Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
liver-expressed antimicrobial peptide 2 (LEAP2)
arcuate nucleus (ARC)
food intake
energy metabolism
proopiomelanocortin (POMC)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.932761/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.932761/full

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