Silencing of Ago-2 Interacting Protein SERBP1 Relieves KCC2 Repression by miR-92 in Neurons

Silencing of Ago-2 Interacting Protein SERBP1 Relieves KCC2 Repression by miR-92 in Neurons

RNA-binding proteins (RBPs) play important roles in modulating miRNA-mediated mRNA target repression. Argonaute2 (Ago2) is an essential component of the RNA-induced silencing complex (RISC) that plays a central role in silencing mechanisms via small non-coding RNA molecules known as siRNAs and miRNA...

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Bibliographic Details
Main Authors: Christian Barbato, Paola Frisone, Laura Braccini, Simona D’Aguanno, Luisa Pieroni, Maria Teresa Ciotti, Caterina Catalanotto, Carlo Cogoni, Francesca Ruberti
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
microRNA
RNA-binding protein
Ago2
KCC2
SERBP1
RNA-induced silencing complex (RISC)
Online Access:https://www.mdpi.com/2073-4409/11/6/1052

Internet

https://www.mdpi.com/2073-4409/11/6/1052

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