Patch-clamp detection of macromolecular translocation along nuclear pores
The present paper reviews the application of patch-clamp principles to the detection and measurement of macromolecular translocation along the nuclear pores. We demonstrate that the tight-seal 'gigaseal' between the pipette tip and the nuclear membrane is possible in the presence of fully...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
1998-01-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000300003 |