The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias
<p>Abstract</p> <p>Background</p> <p>Interim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs). Data Monitoring Committees (DMCs) often undertake such analyses, but their widening role may lead to e...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-03-01
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| Series: | BMC Medical Research Methodology |
| Online Access: | http://www.biomedcentral.com/1471-2288/8/12 |