Physiological assessment of orthostatic intolerance in chronic fatigue syndrome

Abstract Background Orthostatic intolerance-OI is common in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-ME/CFS. We used a 10-min passive vertical lean test as orthostatic challenge-OC and measured changes in vitals and end tidal CO2 (eTCO2). An abnormal physiologic response to OC was identifi...

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Bibliographic Details
Main Authors: Benjamin H. Natelson, Jin-Mann S. Lin, Michelle Blate, Sarah Khan, Yang Chen, Elizabeth R. Unger
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-022-03289-8