Double-negative T cells ameliorate psoriasis by selectively inhibiting IL-17A-producing γδlow T cells

Double-negative T cells ameliorate psoriasis by selectively inhibiting IL-17A-producing γδlow T cells

Abstract Background Psoriasis is a chronic immune-mediated skin condition. Although biologic treatments are effective in controlling psoriasis, some patients do not respond or lose response to these therapies. Thus, new strategies for psoriasis treatment are still urgently needed. Double-negative T...

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Bibliographic Details
Main Authors: Yunxiong Wei, Guangyong Sun, Yang Yang, Mingyang Li, Shimeng Zheng, Xiyu Wang, Xinjie Zhong, Zihan Zhang, Xiaotong Han, Haiyan Cheng, Dong Zhang, Xueling Mei
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Translational Medicine
Subjects:
Psoriasis
γδ T cells
Double Negative T cells
IL-17A
Cell therapy
Online Access:https://doi.org/10.1186/s12967-024-05132-8

Internet

https://doi.org/10.1186/s12967-024-05132-8

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