Extended genomic HLA typing identifies previously unrecognized mismatches in living kidney transplantation

Extended genomic HLA typing identifies previously unrecognized mismatches in living kidney transplantation

IntroductionAntibody mediated rejection (ABMR) is the most common cause of long-term allograft loss in kidney transplantation (KT). Therefore, a low human leukocyte antigen (HLA) mismatch (MM) load is favorable for KT outcomes. Hitherto, serological or low-resolution molecular HLA typing have been a...

Full description

Bibliographic Details
Main Authors: Claudia Lehmann, Sarah Pehnke, Antje Weimann, Anette Bachmann, Katalin Dittrich, Friederike Petzold, Daniel Fürst, Jonathan de Fallois, Ramona Landgraf, Reinhard Henschler, Tom H. Lindner, Jan Halbritter, Ilias Doxiadis, Bernt Popp, Johannes Münch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
HLA typing
HLA mismatch
donor specific antibodies
NGS
epitope matching
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1094862/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1094862/full

Similar Items